Caption: A 35 y/o female, asymptomatic with a liquid based pap smear for routine screening Very slight inflmmation with these cells showing obvious halo with dense chromatin and nuclei (×3 or even more in nuclear size in comparison to adjacent intermediate squamous cells), signed out as "LSIL" and recommended HPV molecular testing Later the test was performed and the patient was positive for high risk HPV (slide 10)